Current just using
JMS_BROKER_MEMORY=1000000000
This solve the problem.
The others you could try
JMS_BROKER_STORAGE=200000000
JMS_BROKER_TEMP_USAGE=200000000
Also as suggested by Rennur look at your memory allocation, we currently have Aware at 25gig, Tomcat at 10gig.
Lastly what is your thread count, have found anything above 120 aware is extremely slow and will eventually cause a JMS out of memory error.